A study reveals that changes in the hippocampus, a key brain area, may determine why some individuals with chronic pain ...

Scientists have uncovered a brain mechanism that may explain why chronic pain leads to depression in some people but not ...

A neuroimaging study in Italy found that patients with bipolar disorder reporting more adverse childhood experiences tended ...

A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor ...

Researchers identify the hippocampus and microglia as the "tipping point" that determines if chronic pain leads to depression or resilience.

Researchers have discovered a surprising change in how cells produce energy in people with depression. Brain and blood cells in young adults with major depressive disorder produced more energy ...

It's widely recognized that psychiatric conditions like depression and anxiety disorders are based in the brain. Scientists have even started to discover which brain areas are involved in different ...

Researchers used a novel PET tracer to visualize how ketamine alters AMPA receptor distribution in the brains of patients with treatment-resistant depression. Receptor density increased in cortical ...

Depression-related fatigue is caused by cellular "overworking" at rest and a failure to produce energy under stress.

A study published in the journal Translational Psychiatry found that brain and blood cells in young adults with depression produced energy at rest but had trouble increasing production when needed -- ...