In advanced cancers, including breast, lung, and melanoma, leptomeningeal disease (LMD), a condition associated with rapid neurological deterioration, can develop. Treatment options remain limited, ...

Building on previous research 1—3 led by Joan Seoane, Director of Translational Research at the Vall d'Hebron Institute of Oncology (VHIO) and ICREA Research Professor, latest findings from a proof-of ...

Researchers from the MPI of Biochemistry and the Technical University of Munich have discovered new diagnostic markers for multiple sclerosis (MS), a disease that affects 3 million people worldwide.

Exploring the genetic blueprint of cerebrospinal fluid proteins, this study uncovers new markers and therapeutic targets that may unlock advancements in Alzheimer’s diagnosis and care. Study: ...

Introduction Onchocerciasis, commonly known as river blindness, is a parasitic disease caused by Onchocerca volvulus affecting millions predominantly in sub-Saharan Africa. Robust epidemiological ...

Comparing rates of immune checkpoint inhibitor toxicity in different treatment settings (neoadjuvant, adjuvant, and palliative) in non-small cell lung cancer (NSCLC): A meta-analysis of phase III ...

“Latent herpes viruses have the potential to reactivate in people living with HIV which can lead to neuroinflammation and impact long-term brain health,” said Shirin Mazumder, MD, infectious diseases ...

Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...

In addition to brain imaging, laboratory analysis of cerebrospinal fluid is important for the diagnosis of multiple sclerosis (MS). In this study, proteomic analysis of this fluid has revealed a set ...

Researchers have identified a set of 22 proteins that distinguish multiple sclerosis from other inflammatory diseases.