T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...
A cluster of recent studies has sharpened the scientific picture of how T cells switch on, tracking the molecular signals ...
Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...
This summer, over 50 researchers in the NSF EMBRIO Institute convened to share their newest findings on cellular signaling and organization that drives wound repair, cellular defense, and organismal ...
P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...
Background High serum levels of interleukin 6 (IL-6) predict poor prognosis in intrahepatic cholangiocarcinoma (iCCA), a malignancy that often develops in a chronically inflamed milieu . Here, tumour ...
In a major brain science breakthrough, New Orleans-based researchers and collaborators have discovered a nerve signaling mechanism that takes place outside the cell, flipping on a 'pain switch.' This ...
How does a single cell reliably build one of the most complex structures known in nature? New research suggests the answer may not depend solely on chemical signals, as long assumed.
A research group led by Professor Cecilia Sahlgren at Åbo Akademi University (Finland) and the InFLAMES Research Flagship has identified a new mechanism directing the adverse remodeling of tumor ...