Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Your endless scroll may be costing you more than just your time. New research shows it’s changing the way you think and make decisions. These days, almost everything is available in the form of quick, ...

A non-intoxicating compound in cannabis could offer a breakthrough treatment for alcohol use disorder. New research shows CBD ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, ...

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...

The ‘gray area’ of addiction.