However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...

B cells are a central component of the adaptive immune system, responsible for recognising pathogens and producing antibodies that neutralise infections. Their development, activation and ...

University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – ...

Memory B cells are particularly long-lived and "remember" pathogens, priming the immune system to respond quickly if it encounters the pathogen again. When someone has cancer or a chronic infection, ...

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody ...

Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

Lingering inflammation from viruses like COVID-19 or HIV can take a lasting toll on the brain. New research shows exactly how specific immune system imbalances lead to memory lapses and slowed ...

Prior exposure to one strain of influenza virus may weaken children's ability to mount an effective antibody response against their subsequent exposure to a different flu strain, according to a study ...

T-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma cells in response to a second infection BIRMINGHAM, Ala. – ...