Researchers identify the Munc13-1 protein as a crucial molecular pathway for working memory, linking calcium signaling to synaptic strengthening.

Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining information. This process enables us to understand information, learn and manage ...

Scientists show that specifying the timing pattern of neurostimulation -- impulses used to activate the brain's own electrical signaling mechanisms -- can rebalance the strength of synaptic ...

Researchers have mapped and catalogued more than 70,000 synaptic connections from about 2,000 rat neurons, using a silicon chip capable of recording small yet telltale synaptic signals from a large ...

Researchers at Johns Hopkins Medicine say they unexpectedly found new information about a protein's special role in getting brain cells to communicate at the right time and place in experiments with ...

Increased levels of bioactive lipids produced naturally in the body, which affect excitatory transmission between brain cells, promote mental disorders. However, this mechanism can be rebalanced by ...

Low-dose ephedrine disrupts synaptic signaling and behavior in adult zebrafish. Schematic overview of the experimental design, key neurotoxic mechanisms, and functional outcomes following chronic ...