Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

A discovery upends decades of assumptions regarding DNA replication. The study show that DNA replication in early embryos is different from what past research has taught, and includes a period of ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that large pieces of DNA ...

Live imaging of embryos at different stages. Chromosomes are labeled in magenta. 4-cell sister blastomeres are shown, along with 3D-reconstructed images of 2-to-4-cell and 4-to-8-cell divisions.