New research shows how cancer cells use a vitamin B7-dependent pathway to survive in the absence of glutamine, revealing potential drug targets.
A new study shows cancer cells depend on vitamin B7 to use pyruvate as backup fuel, opening new strategies for targeted therapy.
Endogenous pyruvate is an end-product in glycolysis and a key molecule for ATP production under aerobic and anaerobic conditions, whereas exogenous pyruvate is transferred to cells via monocarboxylate ...